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By Azita Goshtasebi

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2008) include a large sample of patients, its multicentral nature and the identification of predictors for diagnosis. In addition, their paper presents ED for a large cohort of patients in buprenorphine treatment. Quaglio et al. (2008) conclude that ED is likely to be an important problem for many males in methadone and buprenorphine treatment, and good addiction treatment will need to address this issue. Androgen replacement and pharmacological treatment may be effective approaches for these patients.

Opioid drugs also can induce euphoria by affecting the brain regions that mediate what we perceive as pleasure. This feeling is often intensified for those who abuse opioids, when administered by routes other than those recommended. For example, OxyContin is often snorted or injected to enhance its euphoric effects, while at the same time increasing the risk of serious medical consequences, such as opioids overdose. Many studies have shown that the properly managed, short-term medical use of opioid analgesic drugs is safe and rarely causes addiction - defined as the compulsive and uncontrollable use of drugs despite adverse consequences - or dependence, which occurs when the body adapts to the presence of a drug, and often results in withdrawal symptoms when that drug is reduced or stopped.

Kurz, M. (2003). Buprenorphine versus methadone maintenance treatment in an ambulant setting - a health-related quality of life assessment. 98, pp. 693-702. J. (1981, 1983). The Sex Atlas. New popular Reference Edition Revised and Expanded. Y. , Breen, C. & Davoli, M. (2004). Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database of Systematic Reviews (Online), Vol. 3, CD002207 Mendelson, J. , Inturrisi, C. , Renault, P. & Senay, E. C. (1976): Effects of acetylmethadol on plasma testosterone.

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